Estimate the pka values for the functional group classes represented by the given molecules.

estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445

General guidance

Concepts and reason
value tells the acidic strength of an acid. If value is less than one then the acid is strong and it dissociates completely in water. If value is greater than one then the acid is weak and it dissociates incompletely in water.

Fundamentals

value can be calculated by using the following formula.

Step-by-step

Step 1 of 6

The value of ethanol is

Calculate the value by using the following expression.

Thus, the value of ethanol is around 15.

From the above calculation value of ethanol is 14.88

Substitute the value in expression.

Step 2 of 6

The value of acetic acid is

Calculate the value by using the following expression.

Thus, the value of acetic acid is around 5.

From the above calculation value of acetic acid is 4.76.

Substitute the value in expression.

Step 3 of 6

The value of ethyl ammonium ion is

Calculate the value by using the following expression.

Thus, the value of ethyl ammonium ion is around 10.

From the above calculation value of ethyl ammonium ion is 10.67.

Step 4 of 6

The value of isobutane is

Calculate the value by using the following expression.

Thus, the value of isobutane is around 50.

Alkanes are weak acids. From the above calculation value of isobutane is 10.67.

Step 5 of 6

The value of terminal alkyne is

Calculate the value by using the following expression.

Thus, the value of terminal alkyne is around 25.

Alkynes are weak acids. From the above calculation value of an alkyne is 25.

Step 6 of 6

The value of diethyl amine is

Calculate the value by using the following expression.

Thus, the value of dimethyl amine is around 40.

Amines are weak acids. From the above calculation value of diethyl amine is 40.

Answer

Thus, the value of ethanol is around 15.

Thus, the value of acetic acid is around 5.

Thus, the value of ethyl ammonium ion is around 10.

Thus, the value of isobutane is around 50.

Thus, the value of terminal alkyne is around 25.

Thus, the value of dimethyl amine is around 40.

Answer only

Thus, the value of ethanol is around 15.

Thus, the value of acetic acid is around 5.

Thus, the value of ethyl ammonium ion is around 10.

Thus, the value of isobutane is around 50.

Thus, the value of terminal alkyne is around 25.

Thus, the value of dimethyl amine is around 40.

PK, = -log(K)
1.26×10-15
НО.
PK, = -log(K) = -log(1.26×10-15) = 14.88
1.75×10-5
НО
pK, = -log(K) = -log(1.75×10-) = 4.76
2.12×10-”
NH3
PK, =- log(K) =- log (2.12×10-) = 10.67
1.0×10-50
PK, =- log(K) = -log(1.0×10-5) = 50
1.0×10-25
-C5 -H
PK, = -log(K) = -log(1.0×10-25) = 25
1.0×10-40
I
PK, = -log(K) = -log(1.0×10**) = 40
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estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501 105011050 050 050 0505 505 51122 344 IH 50 15 20 25 30 54 45 50 050505050 5112233445 50 15 20 25 30 35 40 45 050505050 5112233445 050505050 5112233445 -스 050505050 5112233445 sou 50 15 20 25 30 3 4 55 050505050 5112233445 estimate the pKa values for the functional classes represented by the given molecules. C_C_H OH 05 05 05 05 10 10 1 1 01011010 010 10 O 15 015 | 10 1511015 O 15 O 15 020 O 20 0201 102011020 020 020 O 25 025 | |O 25 110 25 025 25 030 0301 103011030 030 030 O 35 035 | 1035 | |O 35 035 035 035 0401 104011040 40 40 40 045 O 45 45 | | O 45 1 10 45 O 45 45 050 0501









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